NuCana welcomes Dr. Elliott Levy to its Board of Directors

– UK, Edinburgh –  NuCana plc (Nasdaq: NCNA), a clinical-stage biopharmaceutical company focused on significantly improving treatment outcomes for patients with cancer today announced the appointment of Dr. Elliott Levy (M.D.) to its Board of Directors, bringing over 20 years of experience at global pharmaceutical companies, including Amgen and Bristol-Myers Squibb, and a strong track record of leading clinical strategy and development efforts for numerous programs at all stages of development.

“We are thrilled to welcome Dr. Levy to our Board of Directors,” said Founder and CEO, Hugh Griffith. “He is a recognized and respected industry veteran and has played a major role in the development of 20 approved medicines during his time at Amgen and Bristol-Myers Squibb. We look forward to his contributions and strategic guidance as we continue to advance our pipeline of ProTides to provide more effective and safer medicines for patients with cancer.”

About Dr. Elliott M. Levy

Dr. Levy was most recently SVP of Global Development and R&D Strategy and Operations at Amgen where he was responsible for managing and executing Amgen’s R&D strategy and drug development process. Previously, Dr. Levy spent 17 years at Bristol-Myers Squibb where he was SVP and Head of Specialty Development and held a range of senior positions in BMS’s research and development group. Before joining BMS, Dr. Levy was a member of the Renal Division at Brigham and Women’s Hospital, where he was an investigator in federally-sponsored outcomes research and industry-sponsored clinical trials. Dr. Levy currently serves as a director for Omega Therapeutics and previously served as Board Chair of TransCelerate BioPharma.

Dr. Levy commented, “I am excited to join NuCana’s Board at this important time in the Company’s growth. I believe that NuCana’s novel ProTide platform represents a new era in oncology and that NuCana has the potential to transform the standards of care for many patients with cancer. I look forward to working with the team as NuCana advances its ProTides through the clinic and, if approved, to commercial launch.”

He received his M.D. from the Yale School of Medicine, where he was Chief Medical Resident focusing on internal medicine and nephrology and completed fellowship training in clinical research through the Robert Wood Johnson Clinical Scholars program.

About NuCana

NuCana is a clinical-stage biopharmaceutical company focused on significantly improving cancer patients’ treatment outcomes by applying our ProTide technology to transform some of the most widely prescribed chemotherapy agents, nucleoside analogs, into more effective and safer medicines. While these conventional agents remain part of the standard of care for the treatment of many solid and hematological tumors, their efficacy is limited by cancer cell resistance mechanisms and they are often poorly tolerated. Utilizing our proprietary technology, we are developing new medicines, ProTides, designed to overcome key cancer resistance mechanisms and generate much higher concentrations of anti-cancer metabolites in cancer cells. NuCana’s robust pipeline includes three ProTides in clinical development. Acelarin and NUC-3373 are new chemical entities derived from the nucleoside analogs gemcitabine and 5-fluorouracil, respectively, two widely used chemotherapy agents. Acelarin is in a Phase 3 study for patients with advanced biliary tract cancer. NUC-3373 is in a Phase 1b/2 study in patients with metastatic colorectal cancer. Our third ProTide, NUC-7738, is a transformation of a novel anti-cancer nucleoside analog (3’-deoxyadenosine) and is in a Phase 1 study for patients with advanced solid tumors.

For more information: http://www.nucana.com/

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