Epizyme appoints Board member Grant Bogle as new CEO

– USA, MA –  Epizyme, Inc. (Nasdaq: EPZM), a fully integrated, commercial-stage biopharmaceutical company developing and delivering novel epigenetic therapies today announced the appointment of industry veteran and Board member Grant Bogle as CEO succeeding Robert Bazemore effective August 9, 2021.

“On behalf of the entire Board of Directors at Epizyme, we welcome Grant into the CEO role. Grant’s extensive commercial expertise, track record of strategic execution and commitment to Epizyme, as demonstrated by his role on the Board, make him well suited to lead the Company forward. We thank Rob for his years of dedication to leading Epizyme through a number of critical milestones to the commercial stage company it is today, and we are confident that with Rob’s support through this transition, Grant will be successful in leading Epizyme through this next phase of growth.” said Board member, David Mott.

“Since 2015, the Epizyme Board has trusted me to lead the Company through a critical period, including the clinical development and FDA approvals for TAZVERIK in two separate indications, launching TAZVERIK during a global pandemic and positioning our pipeline to deliver additional TAZVERIK indications and new early-stage programs like EZM-0414, our novel SETD2 inhibitor,” said current CEO, Robert Bazemore. “Our strategic vision that was rolled out earlier this year remains clear: expand TAZVERIK commercial adoption globally while executing the next phase of the Company’s growth. With the Board’s support, I feel the time is right to hand the reins over to Grant and I am excited to work closely with him to achieve Epizyme’s vision.”

About Grant Bogle

Grant Bogle joined Epizyme’s Board in 2019, bringing deep oncology and senior leadership experience ahead of the approval and launch of TAZVERIK. His appointment to CEO signifies the importance of the first pillar of the Company’s five-year vision: maximizing the adoption of TAZVERIK as a backbone of therapy in Epithelioid Sarcoma (ES) and Follicular Lymphoma (FL) while continuing to broaden its portfolio through new potential TAZVERIK indications and bringing novel epigenetic treatments into clinical development. Importantly, Mr. Bogle brings to his new role significant commercial experience in challenging, competitive markets and has a deep understanding of the oncology provider market.

“Thanks to the leadership of Rob and the hard work of everyone at Epizyme, an incredible foundation has been laid that is positively impacting the lives of FL and ES patients in the U.S. today,” said Grant Bogle. “I speak from personal experience that when you look back on your career, there is nothing more satisfying than knowing you helped deliver groundbreaking therapies to patients in need. Together with the incredible Epizyme team, I will work tirelessly to accelerate the adoption of TAZVERIK in its approved indications and maximize the Company’s portfolio by continuing to advance novel epigenetic programs into the clinic.”

Before joining Epizyme, Mr. Bogle served as SVP and Chief Commercial Officer of TESARO, which was acquired by GlaxoSmithKline plc in 2019, where he oversaw the build-up of the U.S. commercial organization and led the launch of three products, including TESARO’s ZEJULA for ovarian cancer. He was also responsible for TESARO’s global commercial strategy. Earlier, he served as SVP of Sales and Marketing at Millennium Pharmaceuticals, leading the commercialization of VELCADE and establishing it as a foundational therapy in multiple myeloma.

Mr. Bogle also served as SVP of Pharmaceutical and Biotech Solutions at McKesson Specialty Health, where he led numerous businesses that worked closely with oncology-focused companies to engage, educate and support oncologists and patients to access and appropriately utilize their medications. Before the acquisition by McKesson, he was part of the executive leadership team of US Oncology and held roles that allowed him to work directly with the senior physician leadership of The US Oncology Network, which includes some of the largest oncology practices in the country, providing first-hand insight into how physicians make clinical decisions and how payor policies, pathways, and operational work-flow impact therapy selection.

About Epizyme, Inc.

Epizyme, Inc. is a fully integrated, commercial-stage biopharmaceutical company committed to its mission of rewriting treatment for cancer and other serious diseases through novel epigenetic medicines. In addition to an active research and discovery pipeline, Epizyme has one U.S. FDA approved product, TAZVERIK, for the treatment of adults and pediatric patients aged 16 years and older with metastatic or locally advanced epithelioid sarcoma who are not eligible for complete resection; adult patients with relapsed or refractory follicular lymphoma (FL) whose tumors are positive for an EZH2 mutation as detected by an FDA-approved test and who have received at least two prior systemic therapies; and adult patients with relapsed or refractory follicular lymphoma who have no satisfactory alternative treatment options. These indications are approved under accelerated approval based on the overall response rate and duration of response. Continued approval for these indications may be contingent upon verification and description of clinical benefit in a confirmatory trial(s). The Company is also exploring the treatment potential of tazemetostat in investigational clinical trials in other solid tumors and hematological malignancies, as a monotherapy and combination therapy in both relapsed and front-line disease settings. By focusing on the genetic drivers of disease, Epizyme seeks to match medicines with the patients who need them.

For more information: https://www.epizyme.com/

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