– UK, London – Orchard Therapeutics (Nasdaq: ORTX), a leading commercial-stage biopharmaceutical company dedicated to transforming the lives of patients with serious and life-threatening rare diseases through innovative gene therapies, today announced the appointment of John Curnutte, M.D., Ph.D., to its board of directors. Dr Curnutte brings more than 26 years of research and development expertise in both the biotechnology and pharmaceutical sectors.
Mark Rothera, CEO of Orchard, said, “We are at an exciting juncture in our growth as a company as we have an extensive product pipeline with three regulatory filings expected by the end of 2021, making this an opportune time for John to join our Board of Directors. John’s significant research background and experience in advancing medicines through various stages of development and the regulatory approval process will be invaluable to our research and development strategy as we work to bring one-time potentially curative therapies to patients.”
About Dr John Curnutte
Dr. Curnutte has had an extensive career as a clinician, researcher, and drug development executive, bringing with him industry-leading expertise in not only advancing novel therapies through research and development but in working with and treating patients in need. Most recently, he served as executive vice president of research and development for Portola Pharmaceuticals, where he worked as the lead executive officer for all R&D activities. Prior to joining Portola, Dr Curnutte served as CEO at 3-V Biosciences and as president of the research institute at Schering-Plough Biopharma, where he helped progress eight therapeutic candidates into development. He began his biopharmaceutical career at Genentech, where he oversaw their immunology discovery research program. Dr Curnutte’s clinical and research experience include appointments at Massachusetts General Hospital, the Dana-Farber Cancer Institute, University of Michigan Medical School, The Scripps Research Institute and Stanford University School of Medicine. He currently serves on the board of directors of Pliant Therapeutics.
“Orchard has an impressive pipeline of clinical-stage blood stem cell gene therapies,” said Dr Curnutte. “The strength of Orchard’s approach to gene therapy is evidenced by the long-term durability and efficacy data and the number of patients treated across multiple indications with its commercial and investigational therapies. I’m excited to help Orchard on their journey to bring new, potentially curative therapies to patients with rare genetic diseases.”
Dr Curnutte holds an A.B. in Biochemistry and Molecular Biology from Harvard University and an M.D. and a PhD in Biological Chemistry from Harvard Medical School.
About Orchard
Orchard Therapeutics is a fully integrated commercial-stage biopharmaceutical company dedicated to transforming the lives of patients with serious and life-threatening rare diseases through innovative gene therapies.
Orchard’s portfolio of ex vivo, autologous, hematopoietic stem cell-based gene therapies includes Strimvelis, gammaretroviral vector-based gene therapy and the first such treatment approved by the European Medicines Agency for severe combined immune deficiency due to adenosine deaminase deficiency. Additional programs for neurometabolic disorders, primary immune deficiencies and hemoglobinopathies are all based on lentiviral vector-based gene modification of autologous HSCs and include three advanced registrational studies for metachromatic leukodystrophy, ADA-SCID and Wiskott-Aldrich syndrome, clinical programs for X-linked chronic granulomatous disease, transfusion-dependent beta-thalassemia and mucopolysaccharidosis type I, as well as an extensive preclinical pipeline. Strimvelis, as well as the programs in MLD, WAS and TDT were acquired by Orchard from GSK in April 2018 and originated from a pioneering collaboration between GSK and the San Raffaele Telethon Institute for Gene Therapy in Milan, Italy initiated in 2010.
Orchard currently has offices in the U.K. and the U.S., including London, San Francisco and Boston.
For more information: https://www.orchard-tx.com
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