– USA, MA – Syros Pharmaceuticals (NASDAQ: SYRS), a leader in the development of medicines that control the expression of genes, today announced the appointment of Mark Alles to its Board of Directors.
Mr. Alles is a recognized biopharmaceutical executive with a proven record of building successful global oncology organizations and commercializing innovative therapies over his 30-year career.
“Mark is an outstanding leader who drove the growth of Celgene into an oncology powerhouse that delivered important therapies for patients across the world,” said Dr. Nancy Simonian, CEO. “His deep strategic, operational and commercial experience will be invaluable to Syros as we continue to advance toward our vision of being a fully integrated company with medicines that make a profound difference for patients.”
Syros also announced that Vicki L. Sato, Ph.D., has stepped down from the Company’s board of directors.
“On behalf of our board of directors and management team, I want to thank Vicki for her years of service and her many contributions to Syros,” Dr. Simonian said. “We are grateful for her thoughtful guidance and support over the years.”
About Mark Alles
Mr. Alles is the former Chairman and CEO Celgene Corporation, now a subsidiary of Bristol-Myers Squibb Company. In his 16-year tenure at Celgene, Mr. Alles led the expansion of the company from a US-based organization with less than 500 employees into a global enterprise serving patients in more than 50 countries with 8,800 employees. He held a series of commercial and leadership roles of escalating responsibility, consistently delivering industry-leading financial performance. He led teams that completed several multibillion-dollar companies or asset acquisitions, built a diverse suite of globally marketed medicines and a pipeline of high-potential therapeutics for cancer and serious inflammatory diseases, all of which ultimately led to the $74 billion acquisition of Celgene by BMS.
Before joining Celgene, Mr. Alles was Vice President of the U.S. Oncology business unit at Aventis Pharmaceuticals and served in other senior commercial management roles at Aventis. He began his career in the pharmaceutical industry at Bayer and worked at Centocor before its acquisition by Johnson & Johnson. Mr. Alles earned his B.S. degree from Lock Haven University of Pennsylvania and served as a Captain in the United States Marine Corps. Mr. Alles is a former Board member of the Pharmaceutical Research and Manufacturers of America, the European Federation of Pharmaceutical Industries and Associations, the Biotechnology Innovation Organization, Gilda’s Club NYC, and a former member of the Trustees for the Healthcare Institute of New Jersey.
“There is tremendous promise in Syros’ pipeline programs and its pioneering approach for discovering and developing oral medicines to control the expression of genes,” said Mr. Alles. “I look forward to working with the board and the management team to build a great and enduring company that fulfills our shared mission of delivering medical innovation for patients.”
About Syros Pharmaceuticals
Syros is redefining the power of small molecules to control the expression of genes. Based on its unique ability to elucidate regulatory regions of the genome, Syros aims to develop medicines that provide a profound benefit for patients with diseases that have eluded other genomics-based approaches. Syros is advancing a robust pipeline of development candidates, including SY-1425, a first-in-class oral selective RARα agonist in a Phase 2 trial in a genomically defined subset of acute myeloid leukemia patients, and SY-5609, a highly selective and potent oral CDK7 inhibitor in investigational new drug application-enabling studies in cancer. Syros also has multiple preclinical and discovery programs in oncology and monogenic diseases, including sickle cell disease.
For more information : https://www.syros.com
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